Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5′-flanking region of PRDM16 gene associated with lean body mass

Genetic factors are important for the development of sarcopenia, a geriatric disorder characterized by low lean body mass. The aim of this study was to search for novel genes that regulate lean body mass in humans. We performed a large-scale search for 250K single-nucleotide polymorphisms (SNPs) ass...

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Detaylı Bibliyografya
Yayımlandı:Aging Cell
Asıl Yazarlar: Urano, Tomohiko, Shiraki, Masataka, Sasaki, Noriko, Ouchi, Yasuyoshi, Inoue, Satoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2014
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326941/
https://ncbi.nlm.nih.gov/pubmed/24863034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12228
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