Mechanism and modification of bradykinin-induced coronary vasodilation.

In isolated perfused rabbit hearts, bradykinin produced a concentration-dependent decrease in coronary resistance directly associated with biosynthesis and release of prostaglandin-E-like substance. An inhibitor of bradykinin destruction (the nonapeptide SQ-20881) markedly enhanced both the coronary...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Needleman, P, Key, S L, Denny, S E, Isakson, P C, Marshall GROUSI, Missouri 63110
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1975
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432693/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1056012/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.6.2060
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