Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate.

Cultured human endothelial cells synthesize prostacyclin (PGI2), a potent inhibitor of platelet function, when stimulated with histamine, bradykinin, or ATP. Paradoxically, we report that these agonists also induced the rapid and sustained synthesis of platelet-activating factor (PAF) by endothelial...

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Main Authors: McIntyre, T M, Zimmerman, G A, Satoh, K, Prescott, S M
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC423763/
https://ncbi.nlm.nih.gov/pubmed/2862164
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