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Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate.

Cultured human endothelial cells synthesize prostacyclin (PGI2), a potent inhibitor of platelet function, when stimulated with histamine, bradykinin, or ATP. Paradoxically, we report that these agonists also induced the rapid and sustained synthesis of platelet-activating factor (PAF) by endothelial...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: McIntyre, T M, Zimmerman, G A, Satoh, K, Prescott, S M
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1985
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2862164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111957
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