Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate.

Cultured human endothelial cells synthesize prostacyclin (PGI2), a potent inhibitor of platelet function, when stimulated with histamine, bradykinin, or ATP. Paradoxically, we report that these agonists also induced the rapid and sustained synthesis of platelet-activating factor (PAF) by endothelial...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	McIntyre, T M, Zimmerman, G A, Satoh, K, Prescott, S M
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1985
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423763/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2862164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111957
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