Biophysical Studies on Interactions and Assembly of Full-size E3 Ubiquitin Ligase: SUPPRESSOR OF CYTOKINE SIGNALING 2 (SOCS2)-ELONGIN BC-CULLIN 5-RING BOX PROTEIN 2 (RBX2)

The multisubunit cullin RING E3 ubiquitin ligases (CRLs) target post-translationally modified substrates for ubiquitination and proteasomal degradation. The suppressors of cytokine signaling (SOCS) proteins play important roles in inflammatory processes, diabetes, and cancer and therefore represent...

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Publicat a:J Biol Chem
Autors principals: Bulatov, Emil, Martin, Esther M., Chatterjee, Sneha, Knebel, Axel, Shimamura, Satoko, Konijnenberg, Albert, Johnson, Clare, Zinn, Nico, Grandi, Paola, Sobott, Frank, Ciulli, Alessio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Molecular Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326827/
https://ncbi.nlm.nih.gov/pubmed/25505247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.616664
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