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Mechanistic Diversity of Radical S-Adenosylmethionine (SAM)-dependent Methylation
Radical S-adenosylmethionine (SAM) enzymes use the oxidizing power of a 5′-deoxyadenosyl 5′-radical to initiate an amazing array of transformations, usually through the abstraction of a target substrate hydrogen atom. A common reaction of radical SAM (RS) enzymes is the methylation of unactivated ca...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326810/ https://ncbi.nlm.nih.gov/pubmed/25477520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.607044 |
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