Identification of Novel Radiosensitizers in a High-Throughput, Cell-Based Screen for DSB Repair Inhibitors

Most cancer therapies involve a component of treatment which inflicts DNA damage in tumor cells, such as double-strand breaks (DSBs), which are considered the most serious threat to genomic integrity. Complex systems have evolved to repair these lesions, and successful DSB repair is essential for tu...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cancer Ther
Autori principali: Goglia, Alexander G., Delsite, Robert, Luz, Antonio N., Shahbazian, David, Salem, Ahmed F., Sundaram, Ranjini K., Chiaravalli, Jeanne, Hendrikx, Petrus J., Wilshire, Jennifer A., Jasin, Maria, Kluger, Harriet, Glickman, J. Fraser, Powell, Simon N., Bindra, Ranjit S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326563/
https://ncbi.nlm.nih.gov/pubmed/25512618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0765
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi