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Convergent loss of PTEN leads to clinical resistance to a PI3Kα inhibitor
The feasibility of performing broad and deep tumour genome sequencing has shed new light into tumour heterogeneity and provided important insights into the evolution of metastases arising from different clones(1,2). To add an additional layer of complexity, tumour evolution may be influenced by sele...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326538/ https://ncbi.nlm.nih.gov/pubmed/25409150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13948 |
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