Modulation of microRNA editing, expression and processing by ADAR2 deaminase in glioblastoma

BACKGROUND: ADAR enzymes convert adenosines to inosines within double-stranded RNAs, including microRNA (miRNA) precursors, with important consequences on miRNA retargeting and expression. ADAR2 activity is impaired in glioblastoma and its rescue has anti-tumoral effects. However, how ADAR2 activity...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Tomaselli, Sara, Galeano, Federica, Alon, Shahar, Raho, Susanna, Galardi, Silvia, Polito, Vinicia Assunta, Presutti, Carlo, Vincenti, Sara, Eisenberg, Eli, Locatelli, Franco, Gallo, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326501/
https://ncbi.nlm.nih.gov/pubmed/25582055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0575-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados