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Structural biology of presenilin 1 complexes
The presenilin genes were first identified as the site of missense mutations causing early onset autosomal dominant familial Alzheimer's disease. Subsequent work has shown that the presenilin proteins are the catalytic subunits of a hetero-tetrameric complex containing APH1, nicastrin and PEN-2...
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| Publicat a: | Mol Neurodegener |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326451/ https://ncbi.nlm.nih.gov/pubmed/25523933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-59 |
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