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Data mining-based statistical analysis of biological data uncovers hidden significance: clustering Hashimoto’s thyroiditis patients based on the response of their PBMC with IL-2 and IFN-γ secretion to stimulation with Hsp60

The pathogenesis of Hashimoto’s thyroiditis includes autoimmunity involving thyroid antigens, autoantibodies, and possibly cytokines. It is unclear what role plays Hsp60, but our recent data indicate that it may contribute to pathogenesis as an autoantigen. Its role in the induction of cytokine prod...

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Publicat a:Cell Stress Chaperones
Autors principals: Tonello, Lucio, Conway de Macario, Everly, Marino Gammazza, Antonella, Cocchi, Massimo, Gabrielli, Fabio, Zummo, Giovanni, Cappello, Francesco, Macario, Alberto J. L.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326379/
https://ncbi.nlm.nih.gov/pubmed/25408301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0555-y
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