Data mining-based statistical analysis of biological data uncovers hidden significance: clustering Hashimoto’s thyroiditis patients based on the response of their PBMC with IL-2 and IFN-γ secretion to stimulation with Hsp60

The pathogenesis of Hashimoto’s thyroiditis includes autoimmunity involving thyroid antigens, autoantibodies, and possibly cytokines. It is unclear what role plays Hsp60, but our recent data indicate that it may contribute to pathogenesis as an autoantigen. Its role in the induction of cytokine prod...

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Bibliographic Details
Published in:Cell Stress Chaperones
Main Authors: Tonello, Lucio, Conway de Macario, Everly, Marino Gammazza, Antonella, Cocchi, Massimo, Gabrielli, Fabio, Zummo, Giovanni, Cappello, Francesco, Macario, Alberto J. L.
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2014
Subjects:
Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326379/
https://ncbi.nlm.nih.gov/pubmed/25408301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0555-y
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