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The Sclerostin-Independent Bone Anabolic Activity of Intermittent PTH Treatment Is Mediated by T-Cell–Produced Wnt10b

Both blunted osteocytic production of the Wnt inhibitor sclerostin (Scl) and increased T-cell production of the Wnt ligand Wnt10b contribute to the bone anabolic activity of intermittent parathyroid hormone (iPTH) treatment. However, the relative contribution of these mechanisms is unknown. In this...

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Detaylı Bibliyografya
Yayımlandı:J Bone Miner Res
Asıl Yazarlar: Li, Jau-Yi, Walker, Lindsey D, Tyagi, Abdul Malik, Adams, Jonathan, Weitzmann, M Neale, Pacifici, Roberto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326235/
https://ncbi.nlm.nih.gov/pubmed/24357520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2044
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