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Plasmid-determined tetracycline resistance in Streptococcus faecalis: evidence for gene amplification during growth in presence of tetracycline.

The tetracycline (TG)-resistant Streptococcus faecalis strain DS-5Cl harbors two plasmids designated alpha and gamma with molecular masses of approximately 6 and 35 million daltons, respectively. TC-sensitive variants were derived by storing cells at 45 degrees for 2-3 weeks. Analysis of covalently...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Clewell, D B, Yagi, Y, Bauer, B
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1975
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432617/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/807914/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.5.1720
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