Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways

Intrastriatal injection of recombinant adeno-associated viral vector serotype 2/1 (rAAV2/1) to overexpress the neurotrophic factor pleiotrophin (PTN) provides neuroprotection for tyrosine hydroxylase immunoreactive (THir) neurons in the substantia nigra pars compacta (SNpc), increases THir neurite d...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Gene Ther
Autores principales: Gombash, SE, Manfredsson, FP, Mandel, RJ, Collier, TJ, Fischer, DL, Kemp, CJ, Kuhn, NM, Wohlgenant, SL, Fleming, SM, Sortwell, CE
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326069/
https://ncbi.nlm.nih.gov/pubmed/24807806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2014.42
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares