Preferential Targeting of Disseminated Liver Tumors Using a Recombinant Adeno-Associated Viral Vector

A novel selectively targeting gene delivery approach has been developed for advanced hepatocellular carcinoma (HCC), a leading cause of cancer mortality whose prognosis remains poor. We combine the strong liver tropism of serotype-8 capsid-pseudotyped adeno-associated viral vectors (AAV8) with a liv...

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Gepubliceerd in:Hum Gene Ther
Hoofdauteurs: Della Peruta, Marco, Badar, Adam, Rosales, Cecilia, Chokshi, Shilpa, Kia, Azadeh, Nathwani, Devhrut, Galante, Eva, Yan, Ran, Arstad, Erik, Davidoff, Andrew M., Williams, Roger, Lythgoe, Mark F., Nathwani, Amit C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2015
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326028/
https://ncbi.nlm.nih.gov/pubmed/25569358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.052
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