Preferential Targeting of Disseminated Liver Tumors Using a Recombinant Adeno-Associated Viral Vector

A novel selectively targeting gene delivery approach has been developed for advanced hepatocellular carcinoma (HCC), a leading cause of cancer mortality whose prognosis remains poor. We combine the strong liver tropism of serotype-8 capsid-pseudotyped adeno-associated viral vectors (AAV8) with a liv...

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Bibliographic Details
Published in:Hum Gene Ther
Main Authors: Della Peruta, Marco, Badar, Adam, Rosales, Cecilia, Chokshi, Shilpa, Kia, Azadeh, Nathwani, Devhrut, Galante, Eva, Yan, Ran, Arstad, Erik, Davidoff, Andrew M., Williams, Roger, Lythgoe, Mark F., Nathwani, Amit C.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326028/
https://ncbi.nlm.nih.gov/pubmed/25569358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.052
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