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Moderate alcohol induces stress proteins HSF1 and hsp70 and inhibits pro-inflammatory cytokines resulting in endotoxin tolerance(, )

Binge or moderate alcohol exposure impairs host defense and increases susceptibility to infection due to compromised innate immune responses. However there is a lack of consensus on the molecular mechanism by which alcohol mediates this immunosuppression. Here, we show that cellular stress proteins...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Muralidharan, Sujatha, Ambade, Aditya, Fulham, Melissa A., Deshpande, Janhavee, Catalano, Donna, Mandrekar, Pranoti
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325985/
https://ncbi.nlm.nih.gov/pubmed/25024384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303468
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