Nelfinavir Impairs Glycosylation of Herpes Simplex Virus 1 Envelope Proteins and Blocks Virus Maturation

Nelfinavir (NFV) is an HIV-1 aspartyl protease inhibitor that has numerous effects on human cells, which impart attractive antitumor properties. NFV has also been shown to have in vitro inhibitory activity against human herpesviruses (HHVs). Given the apparent absence of an aspartyl protease encoded...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Adv Virol
Hauptverfasser: Gantt, Soren, Gachelet, Eliora, Carlsson, Jacquelyn, Barcy, Serge, Casper, Corey, Lagunoff, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325974/
https://ncbi.nlm.nih.gov/pubmed/25709648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/687162
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