Nelfinavir Impairs Glycosylation of Herpes Simplex Virus 1 Envelope Proteins and Blocks Virus Maturation

Nelfinavir (NFV) is an HIV-1 aspartyl protease inhibitor that has numerous effects on human cells, which impart attractive antitumor properties. NFV has also been shown to have in vitro inhibitory activity against human herpesviruses (HHVs). Given the apparent absence of an aspartyl protease encoded...

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Bibliografske podrobnosti
izdano v:Adv Virol
Main Authors: Gantt, Soren, Gachelet, Eliora, Carlsson, Jacquelyn, Barcy, Serge, Casper, Corey, Lagunoff, Michael
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325974/
https://ncbi.nlm.nih.gov/pubmed/25709648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/687162
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