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Nelfinavir Impairs Glycosylation of Herpes Simplex Virus 1 Envelope Proteins and Blocks Virus Maturation

Nelfinavir (NFV) is an HIV-1 aspartyl protease inhibitor that has numerous effects on human cells, which impart attractive antitumor properties. NFV has also been shown to have in vitro inhibitory activity against human herpesviruses (HHVs). Given the apparent absence of an aspartyl protease encoded...

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Dettagli Bibliografici
Pubblicato in:Adv Virol
Autori principali: Gantt, Soren, Gachelet, Eliora, Carlsson, Jacquelyn, Barcy, Serge, Casper, Corey, Lagunoff, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325974/
https://ncbi.nlm.nih.gov/pubmed/25709648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/687162
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