Nelfinavir Impairs Glycosylation of Herpes Simplex Virus 1 Envelope Proteins and Blocks Virus Maturation

Nelfinavir (NFV) is an HIV-1 aspartyl protease inhibitor that has numerous effects on human cells, which impart attractive antitumor properties. NFV has also been shown to have in vitro inhibitory activity against human herpesviruses (HHVs). Given the apparent absence of an aspartyl protease encoded...

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Detalhes bibliográficos
Publicado no:Adv Virol
Main Authors: Gantt, Soren, Gachelet, Eliora, Carlsson, Jacquelyn, Barcy, Serge, Casper, Corey, Lagunoff, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325974/
https://ncbi.nlm.nih.gov/pubmed/25709648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/687162
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