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The Dictyostelium prestalk inducer differentiation-inducing factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes

Differentiation-inducing factor-1 (DIF-1) is a polyketide that induces Dictyostelium amoebae to differentiate as prestalk cells. We performed a global quantitative screen for phosphorylation changes that occur within the first minutes after addition of DIF-1, using a triple-label SILAC approach. Thi...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Sugden, Chris, Urbaniak, Michael D., Araki, Tsuyoshi, Williams, Jeffrey G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325849/
https://ncbi.nlm.nih.gov/pubmed/25518940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1319
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