Evidence that DIF-1 and hyper-osmotic stress activate a Dictyostelium STAT by inhibiting a specific protein tyrosine phosphatase

STATc becomes tyrosine phosphorylated and accumulates in the nucleus when Dictyostelium cells are exposed to the prestalk cell inducer Differentiation inducing factor 1 (DIF-1), or are subjected to hyper-osmotic stress. We show that the protein tyrosine phosphatase PTP3 interacts directly with STATc...

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Autores principales: Araki, Tsuyoshi, Langenick, Judith, Gamper, Marianne, Firtel, Richard A., Williams, Jeffrey G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671291/
https://ncbi.nlm.nih.gov/pubmed/18305004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.009936
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