Molecular Characterization of the Cytochrome b Gene and In Vitro Atovaquone Susceptibility of Plasmodium falciparum Isolates from Kenya

The prevalence of a genetic polymorphism(s) at codon 268 in the cytochrome b gene, which is associated with failure of atovaquone-proguanil treatment, was analyzed in 227 Plasmodium falciparum parasites from western Kenya. The prevalence of the wild-type allele was 63%, and that of the Y268S (denoti...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ingasia, Luicer A., Akala, Hoseah M., Imbuga, Mabel O., Opot, Benjamin H., Eyase, Fredrick L., Johnson, Jacob D., Bulimo, Wallace D., Kamau, Edwin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325819/
https://ncbi.nlm.nih.gov/pubmed/25583715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03956-14
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