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The Strength of Synergistic Interaction between Posaconazole and Caspofungin Depends on the Underlying Azole Resistance Mechanism of Aspergillus fumigatus

The majority of azole resistance mechanisms in Aspergillus fumigatus correspond to mutations in the cyp51A gene. As azoles are less effective against infections caused by multiply azole-resistant A. fumigatus isolates, new therapeutic options are warranted for treating these infections. We therefore...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Mavridou, Eleftheria, Meletiadis, Joseph, Rijs, Antony, Mouton, Johan W., Verweij, Paul E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325813/
https://ncbi.nlm.nih.gov/pubmed/25583716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04469-14
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