Sialic Acid-Binding Protein Sp2CBMTD Protects Mice against Lethal Challenge with Emerging Influenza A (H7N9) Virus

Compounds that target the cellular factors essential for influenza virus replication represent an innovative approach to antiviral therapy. Sp2CBMTD is a genetically engineered multivalent protein that masks sialic acid-containing cellular receptors on the respiratory epithelium, which are recognize...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Govorkova, Elena A., Baranovich, Tatiana, Marathe, Bindumadhav M., Yang, Lei, Taylor, Margaret A., Webster, Robert G., Taylor, Garry L., Connaris, Helen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325779/
https://ncbi.nlm.nih.gov/pubmed/25534734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04431-14
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