Inter-species pathway perturbation prediction via data-driven detection of functional homology

Motivation: Experiments in animal models are often conducted to infer how humans will respond to stimuli by assuming that the same biological pathways will be affected in both organisms. The limitations of this assumption were tested in the IMPROVER Species Translation Challenge, where 52 stimuli we...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Bioinformatics
Autores principales: Hafemeister, Christoph, Romero, Roberto, Bilal, Erhan, Meyer, Pablo, Norel, Raquel, Rhrissorrakrai, Kahn, Bonneau, Richard, Tarca, Adi L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
Materias:
Improver Challenge Special Issue; Species Translation Challenge
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325539/
https://ncbi.nlm.nih.gov/pubmed/25150249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu570
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares