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ROBO4-Mediated Vascular Integrity Regulates the Directionality of Hematopoietic Stem Cell Trafficking

Despite the use of hematopoietic stem cells (HSCs) in clinical therapy for over half a century, the mechanisms that regulate HSC trafficking, engraftment, and life-long persistence after transplantation are unclear. Here, we show that the vascular endothelium regulates HSC trafficking into and out o...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Smith-Berdan, Stephanie, Nguyen, Andrew, Hong, Matthew A., Forsberg, E. Camilla
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325232/
https://ncbi.nlm.nih.gov/pubmed/25640759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.12.013
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