The Vps39-like TRAP1 is an effector of Rab5 and likely the missing Vps3 subunit of human CORVET

Membrane fusion in the endocytic pathway is mediated by a protein machinery consistent of Rab GTPases, tethering factors and SNAREs. In yeast, the endosomal CORVET and lysosomal HOPS tethering complexes share 4 of their 6 subunits. The 2 additional subunits in each complex – Vps3 and Vps8 for CORVET...

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Bibliographic Details
Published in:Cell Logist
Main Authors: Lachmann, Jens, Glaubke, Elina, Moore, Patrick S, Ungermann, Christian
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2014
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325178/
https://ncbi.nlm.nih.gov/pubmed/25750764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21592780.2014.970840
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