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The Vps39-like TRAP1 is an effector of Rab5 and likely the missing Vps3 subunit of human CORVET
Membrane fusion in the endocytic pathway is mediated by a protein machinery consistent of Rab GTPases, tethering factors and SNAREs. In yeast, the endosomal CORVET and lysosomal HOPS tethering complexes share 4 of their 6 subunits. The 2 additional subunits in each complex – Vps3 and Vps8 for CORVET...
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| Veröffentlicht in: | Cell Logist |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4325178/ https://ncbi.nlm.nih.gov/pubmed/25750764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21592780.2014.970840 |
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