Inhibition of protein synthesis in rabbit reticulocyte lysates by double-stranded RNA and oxidized glutathione: indirect mode of action on polypeptide chain initiation.

In the presence of added double-stranded RNA or oxidized glutathione, protein synthesis in heminsupplemented reticulocyte lysates declines abruptly after 8-12 min of incubation at 30 degrees. The kinetics of amino-acid incorporation are very similar to those seen when lysates incorporation are very...

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Detalhes bibliográficos
Main Authors: Clemens, M J, Safer, B, Merrick, W C, Anderson, W F, London, I M
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC432517/
https://ncbi.nlm.nih.gov/pubmed/805425
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