Small Molecule Inhibitor of Type Three Secretion Suppresses Acute and Chronic Chlamydia trachomatis Infection in a Novel Urogenital Chlamydia Model

Previously, we reported that a compound from a group of thiohydrazides of oxamic acids, CL-55, possessed antichlamydial activity in vitro that was accompanied by a decreased translocation of the type three secretion effector, IncA, into the host cell. In this study, the antichlamydial activity of CL...

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Библиографические подробности
Опубликовано в: :Biomed Res Int
Главные авторы: Koroleva, Ekaterina A., Kobets, Natalia V., Zayakin, Egor S., Luyksaar, Sergei I., Shabalina, Ludmila A., Zigangirova, Naylia A.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324818/
https://ncbi.nlm.nih.gov/pubmed/25695086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/484853
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