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Structure of a soluble super-active insulin is revealed by the nature of the complex between cyanogen-bromide-activated sepharose and amines.

Insulin-like material with elevated insulin specific acitivity is released from insulin-Sepharose in the presence of bovine-serum albumin. The mechanism of release and the chemical nature of this insulin-like material are revealed by the finding that amine-Sepharose is O-Sepharose-N-substituted isou...

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Hlavní autoři: Wilchek, M, Oka, T, Topper, Y J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1975
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC432464/
https://ncbi.nlm.nih.gov/pubmed/1055365
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