A subcutaneous adipose tissue–liver signalling axis controls hepatic gluconeogenesis

The search for effective treatments for obesity and its comorbidities is of prime importance. We previously identified IKK-ε and TBK1 as promising therapeutic targets for the treatment of obesity and associated insulin resistance. Here we show that acute inhibition of IKK-ε and TBK1 with amlexanox t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Reilly, Shannon M., Ahmadian, Maryam, Zamarron, Brian F., Chang, Louise, Uhm, Maeran, Poirier, BreAnne, Peng, Xiaoling, Krause, Danielle M., Korytnaya, Evgenia, Neidert, Adam, Liddle, Christopher, Yu, Ruth T., Lumeng, Carey N., Oral, Elif A., Downes, Michael, Evans, Ronald M., Saltiel, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324568/
https://ncbi.nlm.nih.gov/pubmed/25581158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7047
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