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A subcutaneous adipose tissue–liver signalling axis controls hepatic gluconeogenesis

The search for effective treatments for obesity and its comorbidities is of prime importance. We previously identified IKK-ε and TBK1 as promising therapeutic targets for the treatment of obesity and associated insulin resistance. Here we show that acute inhibition of IKK-ε and TBK1 with amlexanox t...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Reilly, Shannon M., Ahmadian, Maryam, Zamarron, Brian F., Chang, Louise, Uhm, Maeran, Poirier, BreAnne, Peng, Xiaoling, Krause, Danielle M., Korytnaya, Evgenia, Neidert, Adam, Liddle, Christopher, Yu, Ruth T., Lumeng, Carey N., Oral, Elif A., Downes, Michael, Evans, Ronald M., Saltiel, Alan R.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Pub. Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324568/
https://ncbi.nlm.nih.gov/pubmed/25581158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7047
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