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Recent advances in genome mining of secondary metabolite biosynthetic gene clusters and the development of heterologous expression systems in Aspergillus nidulans

Fungi are prolific producers of secondary metabolites (SMs) that show a variety of biological activities. Recent advances in genome sequencing have shown that fungal genomes harbor far more SM gene clusters than are expressed under conventional laboratory conditions. Activation of these “silent” gen...

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Détails bibliographiques
Publié dans:J Ind Microbiol Biotechnol
Auteurs principaux: Yaegashi, Junko, Oakley, Berl R., Wang, Clay C.C.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324552/
https://ncbi.nlm.nih.gov/pubmed/24342965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-013-1386-z
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