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Recent advances in genome mining of secondary metabolite biosynthetic gene clusters and the development of heterologous expression systems in Aspergillus nidulans

Fungi are prolific producers of secondary metabolites (SMs) that show a variety of biological activities. Recent advances in genome sequencing have shown that fungal genomes harbor far more SM gene clusters than are expressed under conventional laboratory conditions. Activation of these “silent” gen...

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Detalhes bibliográficos
Publicado no:J Ind Microbiol Biotechnol
Main Authors: Yaegashi, Junko, Oakley, Berl R., Wang, Clay C.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324552/
https://ncbi.nlm.nih.gov/pubmed/24342965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-013-1386-z
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