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Age-specific population frequencies of amyloidosis and neurodegeneration among cognitively normal people age 50-89 years: a cross-sectional study

BACKGROUND: As treatment of pre-clinical Alzheimer's disease (AD) becomes a focus of therapeutic intervention, observational research studies should recognize the overlap between imaging abnormalities associated with typical aging vs those associated with AD. Our objective was to characterize h...

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Pubblicato in:Lancet Neurol
Autori principali: Jack, Clifford R., Wiste, Heather J., Weigand, Stephen D., Rocca, Walter A., Knopman, David S., Mielke, Michelle M., Lowe, Val J., Senjem, Matthew L., Gunter, Jeffrey L., Preboske, Gregory M., Pankratz, Vernon S., Vemuri, Prashanthi, Petersen, Ronald C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324499/
https://ncbi.nlm.nih.gov/pubmed/25201514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(14)70194-2
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