BPIFB3 Regulates Autophagy and Coxsackievirus B Replication through a Noncanonical Pathway Independent of the Core Initiation Machinery

Enteroviruses require autophagy to facilitate the formation of autophagosome (AP)-like double-membrane vesicles that provide the scaffolding for RNA replication. Here, we identify bactericidal/permeability-increasing protein (BPI) fold-containing family B, member 3 (BPIFB3) as a gene whose silencing...

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Bibliographic Details
Published in:mBio
Main Authors: Delorme-Axford, Elizabeth, Morosky, Stefanie, Bomberger, Jennifer, Stolz, Donna B., Jackson, William T., Coyne, Carolyn B.
Format: Artigo
Language:Inglês
Published: American Society of Microbiology 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324245/
https://ncbi.nlm.nih.gov/pubmed/25491355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02147-14
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