Candida albicans Hypha Formation and Mannan Masking of β-Glucan Inhibit Macrophage Phagosome Maturation

Candida albicans is a major life-threatening human fungal pathogen in the immunocompromised host. Host defense against systemic Candida infection relies heavily on the capacity of professional phagocytes of the innate immune system to ingest and destroy fungal cells. A number of pathogens, including...

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Veröffentlicht in:mBio
Hauptverfasser: Bain, Judith M., Louw, Johanna, Lewis, Leanne E., Okai, Blessing, Walls, Catriona A., Ballou, Elizabeth R., Walker, Louise A., Reid, Delyth, Munro, Carol A., Brown, Alistair J. P., Brown, Gordon D., Gow, Neil A. R., Erwig, Lars P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Microbiology 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324242/
https://ncbi.nlm.nih.gov/pubmed/25467440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01874-14
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