Heat stress induces hsc70/nuclear topoisomerase I complex formation in vivo: evidence for hsc70-mediated, ATP-independent reactivation in vitro.

We previously demonstrated that in murine T cells thermotolerance correlated with heat shock protein 70 (hsp70) synthesis and protection of nuclear type I topoisomerase (topo I). Topo I activity returned to normal levels following heat stress even in cells not rendered thermotolerant by a prior heat...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Ciavarra, R P, Goldman, C, Wen, K K, Tedeschi, B, Castora, F J
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1994
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43241/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.5.1751
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