Dynamics of receptor-operated Ca(2+) currents through TRPC channels controlled via the PI(4,5)P(2)-PLC signaling pathway

Transient receptor potential canonical (TRPC) channels are Ca(2+)-permeable, nonselective cation channels that carry receptor-operated Ca(2+) currents (ROCs) triggered by receptor-induced, phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)]. Within the v...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Mori, Masayuki X., Itsuki, Kyohei, Hase, Hideharu, Sawamura, Seishiro, Kurokawa, Tatsuki, Mori, Yasuo, Inoue, Ryuji
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324076/
https://ncbi.nlm.nih.gov/pubmed/25717302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00022
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