Macrophage depletion ameliorates nephritis induced by pathogenic antibodies

OBJECTIVE: Kidney involvement affects 40–60% of patients with lupus and is responsible for significant morbidity and mortality. Using depletion approaches, several studies have suggested that macrophages may play a key role in the pathogenesis of lupus nephritis. However, “off target” effects of mac...

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Udgivet i:J Autoimmun
Main Authors: Chalmers, Samantha A., Chitu, Violeta, Herlitz, Leal C., Sahu, Ranjit, Stanley, E. Richard, Putterman, Chaim
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323927/
https://ncbi.nlm.nih.gov/pubmed/25554644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2014.11.007
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