Nrf2-ARE Activator Carnosic Acid Decreases Mitochondrial Dysfunction, Oxidative Damage and Neuronal Cytoskeletal Degradation Following Traumatic Brain Injury in Mice

The importance of free radical-induced oxidative damage after traumatic brain injury (TBI) has been well documented. Despite multiple clinical trials with radical-scavenging antioxidants that are neuroprotective in TBI models, none is approved for acute TBI patients. As an alternative antioxidant ta...

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Veröffentlicht in:Exp Neurol
Hauptverfasser: Miller, Darren M., Singh, Indrapal N., Wang, Juan A., Hall, Edward D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323924/
https://ncbi.nlm.nih.gov/pubmed/25432068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.11.008
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