Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors.

We have identified the nucleotide sequence of the cDNA encoding the human counterpart of the mouse gene Plk (polo-like kinase). The sequence of the human gene, PLK, predicts a serine/threonine kinase of 603 aa. Expression of PLK mRNA appeared to be strongly correlated with the mitotic activity of ce...

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Main Authors: Holtrich, U, Wolf, G, Bräuninger, A, Karn, T, Böhme, B, Rübsamen-Waigmann, H, Strebhardt, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC43238/
https://ncbi.nlm.nih.gov/pubmed/8127874
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