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Recombinant Influenza Virus Expressing a Fusion Protein Neutralizing Epitope of Respiratory Syncytial Virus (RSV) Confers Protection without Vaccine-Enhanced RSV Disease

Respiratory syncytial virus (RSV) is the leading cause of viral bronchiolitis in both children and the elderly. There is no vaccine available for the prevention of RSV infection. Here, we generated recombinant influenza virus (PR8/RSV.HA-F) expressing an RSV F(243–294) neutralizing epitope in the he...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Lee, Yu-Na, Hwang, Hye Suk, Kim, Min-Chul, Lee, Young-Tae, Lee, Jong Seok, Moore, Martin L., Kang, Sang-Moo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323669/
https://ncbi.nlm.nih.gov/pubmed/25513755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2014.12.009
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