Recombinant Influenza Virus Expressing a Fusion Protein Neutralizing Epitope of Respiratory Syncytial Virus (RSV) Confers Protection without Vaccine-Enhanced RSV Disease

Respiratory syncytial virus (RSV) is the leading cause of viral bronchiolitis in both children and the elderly. There is no vaccine available for the prevention of RSV infection. Here, we generated recombinant influenza virus (PR8/RSV.HA-F) expressing an RSV F(243–294) neutralizing epitope in the he...

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Détails bibliographiques
Publié dans:Antiviral Res
Auteurs principaux: Lee, Yu-Na, Hwang, Hye Suk, Kim, Min-Chul, Lee, Young-Tae, Lee, Jong Seok, Moore, Martin L., Kang, Sang-Moo
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323669/
https://ncbi.nlm.nih.gov/pubmed/25513755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2014.12.009
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