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Baculovirus-expressed virus-like particle vaccine in combination with DNA encoding the fusion protein confers protection against respiratory syncytial virus

Respiratory syncytial virus (RSV) is a major viral agent causing significant morbidity and mortality in young infants and the elderly. There is no licensed vaccine against RSV and it is a high priority to develop a safe RSV vaccine. We determined the immunogenicity and protective efficacy of combine...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Jong Seok, Kwon, Young-Man, Hwang, Hye Suk, Lee, Yu-Na, Ko, Eun-Ju, Yoo, Si-Eun, Kim, Min-Chul, Kim, Ki-Hye, Cho, Min-Kyoung, Lee, Young-Tae, Lee, You Ri, Quan, Fu-Shi, Kang, Sang-Moo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177292/
https://ncbi.nlm.nih.gov/pubmed/25173478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.08.045
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