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Role of Lamin B1 in Chromatin Instability

Nuclear lamins play important roles in the organization and structure of the nucleus; however, the specific mechanisms linking lamin structure to nuclear functions are poorly defined. We demonstrate that reducing nuclear lamin B1 expression by short hairpin RNA-mediated silencing in cancer cell line...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Butin-Israeli, Veronika, Adam, Stephen A., Jain, Nikhil, Otte, Gabriel L., Neems, Daniel, Wiesmüller, Lisa, Berger, Shelly L., Goldman, Robert D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323489/
https://ncbi.nlm.nih.gov/pubmed/25535332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01145-14
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