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Weight Loss by Ppc-1, a Novel Small Molecule Mitochondrial Uncoupler Derived from Slime Mold

Mitochondria play a key role in diverse processes including ATP synthesis and apoptosis. Mitochondrial function can be studied using inhibitors of respiration, and new agents are valuable for discovering novel mechanisms involved in mitochondrial regulation. Here, we screened small molecules derived...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Suzuki, Toshiyuki, Kikuchi, Haruhisa, Ogura, Masato, Homma, Miwako K., Oshima, Yoshiteru, Homma, Yoshimi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323345/
https://ncbi.nlm.nih.gov/pubmed/25668511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117088
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