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Weight Loss by Ppc-1, a Novel Small Molecule Mitochondrial Uncoupler Derived from Slime Mold

Mitochondria play a key role in diverse processes including ATP synthesis and apoptosis. Mitochondrial function can be studied using inhibitors of respiration, and new agents are valuable for discovering novel mechanisms involved in mitochondrial regulation. Here, we screened small molecules derived...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Suzuki, Toshiyuki, Kikuchi, Haruhisa, Ogura, Masato, Homma, Miwako K., Oshima, Yoshiteru, Homma, Yoshimi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323345/
https://ncbi.nlm.nih.gov/pubmed/25668511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117088
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