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Weight loss by Ppc-1, a novel small molecule mitochondrial uncoupler derived from slime mold.

Mitochondria play a key role in diverse processes including ATP synthesis and apoptosis. Mitochondrial function can be studied using inhibitors of respiration, and new agents are valuable for discovering novel mechanisms involved in mitochondrial regulation. Here, we screened small molecules derived...

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Autori principali: Toshiyuki Suzuki, Haruhisa Kikuchi, Masato Ogura, Miwako K Homma, Yoshiteru Oshima, Yoshimi Homma
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2015-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4323345?pdf=render
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