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Fasting induces ketoacidosis and hypothermia in PDHK2/PDHK4-double-knockout mice
The importance of PDHK (pyruvate dehydrogenase kinase) 2 and 4 in regulation of the PDH complex (pyruvate dehydrogenase complex) was assessed in single- and double-knockout mice. PDHK2 deficiency caused higher PDH complex activity and lower blood glucose levels in the fed, but not the fasted, state....
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| Publicado no: | Biochem J |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4323161/ https://ncbi.nlm.nih.gov/pubmed/22360721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20112197 |
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