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Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice
The effect of pyruvate dehydrogenase kinase-4 (PDK4) deficiency on glucose homeostasis was studied in mice fed a high-fat diet. Expression of PDK4 was greatly increased in skeletal muscle and diaphragm but not liver and kidney of wild-type mice fed the high-fat diet. Wild-type and PDK4(−/−) mice con...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493588/ https://ncbi.nlm.nih.gov/pubmed/18430968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00536.2007 |
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