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LKB1 tumor suppressor: Therapeutic opportunities knock when LKB1 is inactivated

LKB1 is commonly thought of as a tumor suppressor gene because its hereditary mutation is responsible for a cancer syndrome, and somatic inactivation of LKB1 is found in non-small cell lung cancer, melanoma, and cervical cancers. However, unlike other tumor suppressors whose main function is to eith...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genes Dis
Main Authors: Zhou, Wei, Zhang, Jun, Marcus, Adam I.
Format: Artigo
Jezik:Inglês
Izdano: Chongqing Medical University 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323096/
https://ncbi.nlm.nih.gov/pubmed/25679014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2014.06.002
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