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Energizing the search to target LKB1-mutant tumors
LKB1 is the 3(rd) most frequently mutated gene in non-small cell lung cancer (NSCLC) and serves as a master regulator of cell metabolism and polarity across a variety of model organisms. Recent studies are beginning to identify therapeutics that exploit defects associated with LKB1 loss. The work pr...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3743546/ https://ncbi.nlm.nih.gov/pubmed/23928772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0296 |
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